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You are What Your Mother Eats: Higher Choline Means Lower Cortisol For Baby

DNA-molecule2

DNA-molecule2 (Photo credit: Wikipedia)

Choline (a nutrient found in  beef liver, chicken liver, eggs, bacon and pork) status in pregnant moms has been found to affect cortisol levels in newborns. According to a study published by Jiang X, Yan et al., http://lib.bioinfo.pl/paper:22418088, these pregnant women were given either 930 or 480 mg/day of choline in their third trimester for 12 weeks. The more choline consumed the more was found in moms blood the lower the levels of stress hormone cortisol was found in baby. As you can see from the chart below, current recommendations need to be updated and increased to help promote healthy gene expression and reduce the risk of unwanted health issues.
The Linus Pauling Institute, http://lpi.oregonstate.edu/infocenter/othernuts/choline/ posted the chart on the Adequate Intake level for choline, however this is not based on the methylation information we now have.

Adequate Intake (AI)               for Choline

Life stageAgeMales (mg/day)Females (mg/day)
Infants0-6 months125125
Infants7-12 months150150
Children1-3 years200200
Children4-8 years250250
Children9-13 years375375
Adolescents14-18 years550400
Adults19 years and older550425
PregnancyAll ages450
Breast-feedingAll ages550

High levels of cortisol is linked to:
Belly fat
Blood sugar imbalances
Anxiety and depression
High Blood pressure
Muscle weakness
Impaired cognitive performance
Lower thyroid function
Decreased bone density
Cancer
It seems that  like choline in this study, other nutrients are classified as “methyl donors” folic acid, vitamin B-12, methionine, and betaine all cross the placenta to affect DNA methylation** in baby which in turn affects your genetics and health issues throughout life.
Additionally other nutrients that have similar effects include tea catechins (green tea),  resveratrol (wine and peanuts), butyrate (butter), sulforaphane (broccoli) , and diallyl sulfide  (garlic), curcumin (curry).  These nutrients may change the way enzymes function therefore affecting whether of not we are more vulnerable to certain illnesses throughout our lives.
It is my personal opinion that practical advice on incorporating these nutrients into your daily diet, especially for moms and women who are thinking about having children, should be given by healthcare experts and medical organizations.
Current focus on food groups are important but with the BIG push to eat low-fat and avoid too much weight gain while pregnant, critical components to having healthy babies, kids and adults get lost.
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** What is methylation?  The perfect answer is described at Curiosity.com from Discovery, http://curiosity.discovery.com/question/what-is-methylation. “Methylation is a process by which a gene’s behavior is altered, but the gene itself isn’t changed.”
The site explains, “This is almost like following all the directions in baking a batch of cookies correctly, except for the oven temperature. Even though all of the ingredients are the same, those cookies won’t bake — or behave — the same way when baked a couple hundred degrees lower than they should be.”
“In methylation, though, the wrong oven temperature is actually other factors, such as environmental exposures or different lifestyle choices. These factors have the potential to cause methyl groups, which are groups of one carbon and three hydrogens, to land on top of our genes and change how they are expressed. This, in turn, changes the ability of our genes to share the directions they contain for making our bodies’ proteins.”

About the author

Valerie Goldstein

Valerie raises the bar for health and nutrition know how with unconventional expertise and unconditional support for wellness.

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